![]() Within a month of the procedure, the researchers noticed that the patients started to show signs of recovery, and such improvements continued over several months. SB623 cells are mesenchymal stem cells (MSCs) that have been taken from the bone marrow of two donors and modified to boost brain function.Īfter the procedure, each patient was monitored through brain imaging, blood tests, and clinical evaluations. All participants had motor function disability as a result of their stroke some patients were unable to move their arm, while others were unable to walk.Įach patient underwent stem cell transplantation, which involved drilling a hole into the skull and injecting stroke-damaged areas of the brain with SB623 cells. ‘Patients who were in wheelchairs are walking now’įor their study, the team enrolled 18 individuals – of an average age of 61 – who had experienced a first stroke 6 months to 3 years previously. But in the new study, researchers found stem cell transplantation improved patients’ recovery when administered up to 3 years after stroke. If the treatment is not received in time, the chance of a full recovery from stroke is small. Steinberg and colleagues note is often exceeded by the time it takes for a patient to arrive at the hospital. However, tPA needs to be administered within hours of stroke occurrence, in order to maximize the likelihood of recovery – a time period that Dr. It works by dissolving the blood clot that is blocking blood flow to the brain. There are treatments available for stroke, such as tissue plasminogen activator (tPA) – considered the “gold standard” treatment for ischemic stroke. Some individuals may experience temporary arm or leg weakness, for example, while others may lose the ability to speak or walk.Īccording to the National Stroke Association, around 2 in every 3 stroke survivors will have some form of disability, and stroke is the leading cause of disability among American adults. Hemorrhagic stroke accounts for around 13 percent of all strokes, arising from leaking or ruptured blood vessels in the brain.Įxactly how stroke affects a person is dependent on what side of the brain it occurs and the amount of damage it causes. It occurs when the flow of oxygen-rich blood to the brain becomes blocked, primarily due to blood clots. ![]() Ischemic stroke is the most common form, accounting for around 87 percent of all strokes. In the United States each year, more than 795,000 people have a new or recurrent stroke. While the trial only included a small number of stroke participants, the results have been met with much positivity, with some health experts claiming the findings could lead to “life-changing treatments” for stroke patients. Gary Steinberg, professor and chair of neurology at Stanford University School of Medicine in Palo Alto, CA, and colleagues publish their findings in the journal Stroke. Share on Pinterest Researchers found that injecting SB623 stem cells into stroke-damaged brain areas restored motor function for patients.
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